Pdf a paper reporting findings relevant to safety of the genetically modified gm maize nk603 and the herbicide roundup. Mon 863, mon 810 and nk603 assessment of quality and response to technical issues synopsis. Consequently, the regulatory status of nk603, glyphosate and roundup requires reevaluation. First published by food and chemical toxicology in september 2012, the article presented a twoyear feeding study in rats, and reported an increase in tumors among rats fed genetically modified corn and the herbicide roundup. Seralinis 2012 study1 tested the longterm effects of monsantos gm nk603 maize, which is engineered to survive being sprayed with roundup herbicide, and roundup. Gilleseric seralini has said from the start that he is reluctant to hand over more information about his recently published study on the impact of nk603 gm maize and monsantos herbicide roundup unless the regulators release ideally on a public website all the health and environmental risk studies on gmos and roundup, including all. During a twoyear study, originally published in the journal food and chemical toxicology, professor gilleseric seralini of the university of caen and colleagues discovered that rats fed monsantos roundup ready corn developed significantly more tumors than rats not fed gm corn. The eufunded study was published in 2019 by pablo steinberg and colleagues and reported the results of the 2year rat feeding study, called gtwyst, on a gm roundup. This was the first study to investigate effects of a roundup for mulation. We appreciate your integrity and professional standards. Their major common phenotypic trait for which 99% have been modified is that these are designed to be grown with pesticides, which may bioaccumulate in the plants andor the consumer, andor express insecticides in their cells.
Levels of carbohydrates even fell under equivalence category iii and differences in calcium under category iv. This retraction is to the antigmo world what the retraction of the infamous wakefield. Long term toxicity of a roundup herbicide and a roundup. Poulter, 2012, much longer study of twoyears duration on nk603 herbicidetolerant corn which contains one of the genes fed in the present study has been published seralini et al. Reactions to republication of landmark seralini gmo study. The maize grown mon006036 com monly named nk603 was authorized for. The incredible seralini affair hello dear reader, in this installment i want to share with you something i have written on one of the most shocking corruption scandals in the history of a very corrupt european union commission together with corruption by monsanto and the related gmo agribusiness industry. Our molecular profiling results show that nk603 and its isogenic control are not substantially equivalent. Introduction the safety of gm food and monsantos herbicide roundup has once more been put into question following the study published on 19 september in the us scientific journal food and chemical toxicology assessing the toxicity of monsantos gm rounduptolerant maize nk603, roundup herbicide and the two combined, on rats1.
It was established to protect africas biodiversity, traditional knowledge, food production systems, culture and diversity, from the threats posed by genetic engineering in food and agriculture. Maize mon 87427 x mon 87460 x mon 89034 x mir162 x nk603. Hayes, i am writing to you in regard to the recent release of a paper to be published in the journal of food and chemical toxicology. Pdf this paper examines biotechnology debates in light of a. The first tumours only appeared four months into the study, one month after. In thissense, eseu aims to enable rational discussions dealing with the article from g. A scientific analysis of the rat study conducted by gilles. The health effects of a rounduptolerant nk603 genetically modified gm maize from 11% in the. Critical remarks on the longterm feeding study by seralini. A longterm toxicology study on pigs fed a combined. Jun 24, 2014 one field of nk603 was treated with r at 3 l ha. If they had been faulty, that would have been good grounds for the retraction.
In seralini s study, the differences are so large that it is not necessary to use a statistical test. After several months of consumption of an rtolerant soy. I do not believe that was your intent and now you have stated what the intent is. European studies disprove seralinis gmo maize tumor. There were indications of higher death rates, more tumours and liver and kidney pathologies in gmfed rats. This study used more rats in test groups, for a far longer duration, than any previous investigation employed by industry to obtain approval for nk603 gm maize and other gm crop products. For maize mon 87427 x mon 89034 x nk603 treated with glyphosate. Efsa hypocrisy, double standards and dodgy dealing on. Seralini study on gmo toxicity disappears after one day online. Gm maize nk603 11, 22, 33 % in the standard diet and gm maize nk 603 11, 22, 33% treated with roundup weathermax during cultivation. Nk603 is the name of a genetic trait tolerance to the herbicide glyphosate introduced into maize corn by transgenesis. Feeding study in rats with genetically modified nk603. A few weeks ago, gilleseric seralini and his homeopathy loving coauthor published an article in food and chemical toxicology that concluded that glyphosate known as roundupresistant nk603 gmo corn, developed by monsanto, causes severe diseases such as tumors in rats. Gilleseric seralini c with dr joel spiroux r and mep corinne lepage afp photokenzo tribouillardwith just a few articles, these journalists set off a media firestorm that renewed concerns about gm foods and forced the mainstream scientific establishment onto the defensive.
A nature editorial called it a publicrelations offensive. Hopefully people supporting seralini will not interpret this deletion as hiding anything. Pdf a case study of gmo research, policy, and regulation. There is a significant difference in concentration from the 1st to the 2nd sample a difference of a. The gm maize alone was tested on three groups at 11%, 22% and 33% of the total diet. An integrated multiomics analysis of the nk603 rounduptolerant. The result of the confidentiality agreement, the journal said, was that critical commentary was absent from the first round of stories, the ones most likely to be remembered. Corn cobs were harvested when the moisturecontent was less than 30% and were dried at a temperature below 30c. Seralini, is a french professor, whom i mentioned earlier. Glyphosate tolerant genetically modified gm maize nk603 was assessed as. French study seralini et al on genetically modified corn. Seralini, you may not realize how many of us have your back.
Prior publications by seralini and colleagues in both the pesticide and gm crops arenas have. Republication of retracted seralini study gm free cymru. The efsa has since published monsantos safety data on nk603 maize, but not on glyphosate. There is a significant difference in concentration from the 1st to the 2nd sample a difference of a factor 107. The identity of nk603 was confirmed by polymerase chain reaction pcr analysis. Nk603 is a variety of roundup ready corn made by monsanto that was deregulated in the u. French academies of science, monsanto, seralini and nk603 gmo. The most pronounced metabolome differences between nk603 and its isogenic counterpart consisted of an increase in polyamines including nacetylcadaverine 2. One field of nk603 was treated with r at 3 l ha 1 weather max, 540 gl of glyphosate, epa reg. In secret internal monsanto documents released on tuesday 1st august.
The ecologist website is a free service, published by the resurgence trust, a ukbased educational charity. Even though the only commercially grown genetically modified crop in europe is corn maize, roundup is still. French academies of science, monsanto, seralini and nk603. Full reasoning of the jury for the 2015 whistleblower. Corns were harvested when the moisture content was less than 30% and were dried at a temperature below 30 c. A diet that contained no genetically modified maize, but in which the rats had free access to drinking water that contained concentrations of the herbicide roundup. Pdf update on longterm toxicity of agricultural gmos. The nk603 maize has been engineered to express a modified version of. Transcriptomics showed no segregation of nk603 maize and control feed groups with false discovery rates ranging from 43 to 83% at a cut. Nk603 produces the cspb protein, derived from bacillus subtilis, which provides reduced yield loss under waterlimited conditions compared to conventional maize. Metabolomics identified 692 and 673 metabolites in kidney and liver, respectively.
Jan 28, 2016 a study into longterm observational data by seralini shows that gm bt176 maize is most probably toxic in animals but the paper has since disappeared from the online journal after only one day online. French academies of science, monsanto, seralini and nk603 gmo corn in an unsigned pdf published on the internet, six french academies agriculture, medicine, pharmacy, sciences, technology, and veterinary declared that they did not need to conduct an expertise approfondie into seralinis study of montanto nk603 gmo corn because studies. The nk603 maize has been engineered to express a modified version of the agrobacterium tumefaciens strain epspscp432. Date added to website 25th june 2014 gm free cymru welcomes the republication of this important study, which was retracted last year from fct journal following a coordinated and vicious campaign of vilification and dafamation directed at prof gilleseric seralini and his fellow researchers by the assembled ranks of the gm industry and its acolytes. The nk603 data are in a pdf format preventing an easy statistical reanalysis. Mon 87427 x mon 89034 x nk603 not treated with glyphosate, statistically significant differences with the nongm comparator were identified for 42 grain endpoints. From these three cultivations of maize, laboratory rat chow was made based on the. Seralinis team and their methodology were found to be honest and sound. Three of these groups received the gm maize nk603 one test group each with 11, 22 and 33% maize in the standard diet and three received gm maize nk603 treated with roundup one test group each with 11, 22 and 33% maize in the standard diet. In addition, rats fed a gmo diet developed aggressive tumors and died sooner than rats in the control group. In that brief, abne clearly articulated views by experts and competent national and international. However, there was no longterm toxicological assessment for nk603, or for roundup. Gmo seralini is a onestop resource for information about the research of gilleseric seralini and colleagues on genetically modified foods and roundup. Three additional groups received 33 % of conventional maize, but this time the drinking water contained 1, 1 % x io8, 0.
The retraction comes one year after the paper was published, and seems to be a response to the avalanche of criticism the study has faced. The control and reference grains tested negative for nk603. From thesethree cultivations of maize, laboratory rat chow was made based on the. The editor of the journal food and chemical toxicology fct, dr a. John fagan1, terje traavik 2,3 and thomas bohn2 abstract a paper reporting findings relevant to safety of the genetically modified gm maize nk603 and the herbicide roundup seralini et al. The seralini gmo study retraction and response to critics. In secret internal monsanto documents released on tuesday 1st august 2017 by legal firms in the u. Faqs on seralini s gm nk603 maize and roundup study. The health effects of a rounduptolerant nk603 genetically modified gm maize from 11% in the diet, cultivated with or without roundup application and roundup alone from 0. Seralini found that gm maize and residues of the roundup herbicide sprayed on the crop were toxic to the laboratory rats and their findings are now validated by this republication in a. Seralini, i do not know if you will ever see this message, but i hope that you do. Jun 24, 2014 one field of nk603 was treated with r at 3 lha. Corn cobs were harvested when the moisture content was less than 30% and were dried at a temperature below 30c. Update on longterm toxicity of agricultural gmos tolerant to.
In a study published in food and chemical toxicology researchers led by gilleseric seralini from criigen have found that rats fed on a diet containing nk603 roundup tolerant gm maize or given water containing roundup, at levels permitted in drinking water and gm crops in the us, developed cancers faster and died earlier than rats fed on a standard diet. It was concluded that there were no adverse effects related to the administration of the gm maize nk603 cultivated with or without roundup, the report stated. The ethics of the seralini retraction and charges of conflict. Long term toxicity of a roundup herbicide and a rounduptolerant genetically modified maize. Wallace hayes, has decided to retract the study by the team of prof gilleseric seralini, which found that rats fed a monsanto genetically modified gm maize nk603 and tiny amounts of the roundup herbicide it is grown with suffered severe toxic effects, including kidney and. Changes in gene expression were not reflective of liver and kidney toxic effects. Journal retraction of seralini study is illicit, unscientific. A paper reporting findings relevant to safety of the genetically modified gm maize nk603 and the herbicide roundup seralini et al. Elsevier has announced that they are retracting the infamous seralini study which claimed to show that gmo corn causes cancer in laboratory rats. The study used 200 rats divided into ten groups, each of ten males and ten females. Hyping the reputation of a scientist or a team is a serious misdemeanor when it helps to spread. It has been genetically engineered to survive being sprayed with the herbicide glyphosate, the active ingredient in monsantos herbicide roundup. Both gm maize nk603 and roundup caused serious kidney and liver damage and an increased and earlier development of large palpable tumours, leading to an increased rate of mortality. The genetically modified maize nk603, roundup and the two in combination were also reported to increase mortality and tumor incidence.
It was established to protect africas biodiversity, traditional knowledge, food production systems, culture and diversity, from the threats posed by. The research included a combined chronic toxicity and carcinogenicity study, and no toxicologically relevant effects related to the gm maize nk603 or the gm maize nk603 treated. Long term toxicity of a roundup herbicide and a rounduptolerant genetically modi. Agricultural genetically modified organisms gmos are plants obtained by gene transfer or more recently by geneediting. African centre for biosafety the african centre for biosafety acb is a non pro. The health effects of a rounduptolerant nk603 genetically modified gm. He carried out experiments on roundup ready corn maize and also on roundup.
Part one january 14, 2014 writing for the hasting centers bioethic forum blog, adriane fughberman and thomas g. All earlier studies investigated glyphosate, the herbicidal ingredient of roundup, in isolation. Seralini found that rats that consumed nk603 corn developed tumors more often than. Seralini calls for retraction of biased eu study on gm. Transgenic lines carrying this trait were, for example, grown in the united states and were authorised for importation into europe.